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Pre-prints

125.  J. Johns, M. Mahanti,* M.C. Galan*

 

“Hypervalent Chalcogenonium H-Bonding Organocatalysis for the Direct Stereoselective Synthesis of Deoxyglycosides”

 

 

ChemRxiv. 2024; doi:10.26434/chemrxiv-2024-26z3t 

 

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122.  J. Ramos-Soriano,* Y.J. Jiang, B. Deng, M. O’Hagan, S.  Haldar, A. Grao, S. OIiveira, A. Mulholland, M.C. Galan*

 

“A bridged azobenzene derivative exhibits fully-reversible photocontrolled binding to a G-quadruplex DNA/duplex junction”

 

ChemRxiv. 2024; doi:10.26434/chemrxiv-2024-7056b 

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2024

123.   Y.Y. Zhang, M. Ghirardello, R. Williams, A. Silva-Diaz, J. Rojo, J. Ramos-Soriano, J. VoglmeirM.C. Galan*

 

“Microfluidics-based Ionic Catch and Release Oligosaccharide Syn-thesis (ICROS-microflow) to expedite glycosylation chemistry”

 

 

JACS Au 2024, Accepted

 

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122.   J. Ramos-Soriano*, M. Holbrow-Wilshaw, E. Hunt, Y.J. Jiang, P. Peñalver,  and, J.C. Morales*, M.C. Galan*

 

“Probing the binding and antiparasitic efficacy of azobenzene G-quadruplex ligands to investigate G4 ligand design”

 

 

Chem Commun. 2024, Advanced Article

DOI: 10.1039/D4CC03106G. 

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121.  K. Hollingsworth , A. Di Maio, S.J. Richards, J. B. Vendeville J-B, M.C. Galan, T. Feizi, M. I. Gibson, Y. Liu, W. B. Turnubull, B. Linclau* et al.

 

“Synthesis and screening of a library of Lewisxdeoxyfluoro-analogues reveals differential recognition by glycan-binding partners”

 

Nature Communications 2024 15, Article number: 7925 (2024)

DOI:10.1038/s41467-024-51081-7

 

“A ‘glyco-fluorine’ code revealing differential recognition by glycan binding partners.”

ChemRxiv 2023; doi:10.26434/chemrxiv-2023-4hn6k 

 

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120.  M.Pérez-Soto, J. Ramos-Soriano, P. Peñalver, 

E. Belmonte-Reche, M. P. O’Hagan, J.-L. Mergny,  M. C. Galan*, M. C. Lopez-Lopez,* M. C. Thomas,* and, J.C. Morales*

"DNA G-quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease: Dithienylethene ligands as effective

antiparasitic agents"

Eur. J. Med. Chem. 276 (2024) 116641 

DOI:10.1016/j.ejmech.2024.116641

ChemRxiv. 2024; doi:10.26434/chemrxiv-2024-wkn1x 

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119. YY.-Y. Zhang, S.-Y. Zhang, Z.-X. Hu, J. Voglmeir, L. Liu,* M. C. Galan,* and M. Ghirardello* 

"High sensitivity profiling of N-glycans from mouse serum using fluorescent imidazolium tags by HILIC electrospray ionisation spectrometry"

Carbohydr. Polym. (2024), 122449

DOI:10.1016/j.carbpol.2024.122449

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118. Y. Takebayashi, J. Samphire, M. P. O’Hagan, C. Gurr, K. J. Heesom, P. A. Lewis, J. Spencer*, M. C. Galan*

"An Azobenzene G-quadruplex Ligand Exhibits Promising Antibacterial Activity against Escherichia coli"

bioRxiv 2022,2022.2009.2001.506212. 

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117. M. Mahanti*, K. B. Pal*, C. J. Wallentin* and  M. C. Galan*

"Hypervalent Iodine Compounds in Carbohydrate Chemistry: Glycosylation, Functionalization and Oxidation"

Chem. Eur. J.  (2024), e202400087 

DOI:10.1002/chem.202400087

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2023

116. T. Keenan, N. E. Hatton, J. Porter, J.-B. Vendeville, D. E. Wheatley, M. Ghirardello, A. J. C. Wahart, 
S. Ahmadipour, J. Walton, M. C. Galan, B. Linclau, G. J. Miller*and M. A. Fascione *

 

"Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manß1,4GlcNAc library."

Chemical Science, 2023, 14, 11638 - 11646

DOI:10.1039/d3sc04169g

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115. T. Garcia-Millan, J. Ramos-Soriano, M. Ghirardello,  X. Liu, C. Manuela Santi, J.-C. Eloi, N. Pridmore​, R.L. Harniman, D. J. Morgan, K. Kurian,  M. C. Galan*.

 

"Multicolour  Photoluminescent Carbon Dots à la carte for biomedical applications."

ACS Appl. Mater. Interfaces 2023, 15, 38, 44711–44721

DOI:org/10.1021/acsami.3c08200

ChemRxiv. DOI: doi.org/10.26434/chemrxiv-2023-bvncz. 

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114. V. Libera, F.  Ripanti, C. Petrillo, F. Sacchetti, J. Ramos-Soriano, M. C. Galan, G. Schirò, A. Paciaroni, L. Comez

 

"Stability of Human Telomeric G-Quadruplexes Complexed with Photosensitive Ligands and Irradiated with Visible Light"

Int. J. Mol. Sci. 2023, 24(10), 9090; 

DOI: org/10.3390/ijms24109090

113. R. E. Nuttall, T. T. Pham, A. C. Chadwick, I. N. Hungnes, G. Firth, M. A. Heckenast, H. A. Sparkes, M. C. Galan*, M. T. Ma*, P. G. Pringle*

 

“Diphosphine Bioconjugates via Pt(0)-Catalyzed Hydrophosphination. A Versatile Chelator Platform for Technetium-99m and Rhenium-188 Radiolabeling of Biomolecules”

 

Inorg Chem (2023), ASAP

DOI: org/10.1021/acs.inorgchem.2c04008

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2022

112. J. Samphire^, Y. Takebayashi^, S. A. Hill, N. Hill, Kate J. Heesom, P. A. Lewis, D. Alibhai, E. C. Bragginton, J. Dorh, N. Dorh, J. Spencer*, M. Carmen Galan*

"Green Fluorescent Carbon Dots as Targeting

Probes for LED-Dependent Bacterial Killings"

 

Nano Select (2022), 3, 662–672.

DOI: 10.1002/nano.202100183

Preprint: (2021) BioRxiv. 

DOI: 10.1101/2021.03.26.437036

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111. J. Ramos-Soriano^*, M. Ghirardello^ and M. Carmen Galan*

"Recent Advances on Multivalent Carbon Nanoform-based Glycoconjugates"

Current Medicinal Chemistry (2022), 29, 7, 1232 

DOI:10.2174/0929867328666210714160954

 

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110. J. Ramos-Soriano*,  Ghirardello* and M. C. Galan* 

"Carbon-based glyco-nanoplatforms: towards the next generation of glycan-based multivalent probes"

Chem. Soc. Rev. (2022), 51, 9960-9985 

DOI:https://doi.org/10.1039/D2CS00741J

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109 R. Jeanneret, C. Walz, M. van Meerbeek, S. Coppock, and M. C. Galan*

"AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives"

Org. Lett., (2022), 24, 34, 6304–6309

DOI:/10.1021/acs.orglett.2c02530

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108. M. Ghirardello*, M. C. Galan 

"Recent applications of ionic liquid-based tags in glycoscience"

Carbohydr. Res. 2022, 520,108643,

DOI:org/10.1016/j.carres.2022.108643

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107. M. Pérez-Soto, P. Peñalver P, S.T.G. Street, D. Weenink, M. P. O'Hagan, J. Ramos-Soriano, Y.J. Jiang, G. J. Hollingworth, M.C. Galan* and, J.C. Morales

Structure-activity relationship studies on divalent naphthalene diimide G quadruplex ligands with anticancer and antiparasitic activity.

 

Bioorg Med Chem. (2022), 71:116946. 

DOI:/10.1016/j.bmc.2022.116946

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106. N. M. C. Mulkerns, W. H. Hoffmann, J. Ramos-Soriano, N. de la Cruz,c T. Garcia-Millan, R. L. Harniman, I. D. Lindsay, A. M. Seddon, M. C. Galan and H. Gersen*

"Measuring the Refractive Index and Sub-Nanometre Surface Functionalisation of Nanoparticles in Suspension"

Nanoscale, (2022), 14, 8145-8152 

DOI:/10.1039/D2NR00120A

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105. M. Ghirardello, R. Shyam and  M. C. Galan* 

 

"Reengineering of cancer cell surface charges can modulate cell migration"

 

Chem. Commun., (2022), 58, 5522-5525

DOI: 10.1039/D2CC00402J

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104. T. Garcia-Millan, T.A. Swift, D.J. Morgan, R.L. Harniman, B. Masheder, S. Hughes, S.A. Davis, T.A.A. Oliver and  M. C. Galan*

"Small variations in reaction conditions tune carbon dot fluorescence"

Nanoscale, (2022), 14, 6930-6940  DOI: 10.1039/D2NR01306A

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103. S. Johnson and M. C. Galan*

"Synthesis of 2-Deoxy Mucin-type O-glycan analogues as Biological Probes"

Carbohydr. Res. 514 (2022) 108542 DOI:10.1016/j.carres.2022.108542

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102. M. Ghirardello, R. Shyam, X. Liu, T. Garcia-Millan, I. Sittel, F. J. Ramos-Soriano, K. Kurian and M. C. Galan*

"Carbon Dot-based Fluorescent Antibody Nanoprobes as Brain Tumour Glioblastoma Diagnostics"

Nanoscale Adv. (2022), 4, 1770 

DOI: 10.1039/D2NA00060A

Preprint: bioRxiv 2021.11.29.470408

DOI:10.1101/2021.11.29.470408ACS

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101. J. B. Vendeville, M. J. Kyriakides, Y. Takebayashi, S. Rama, J. Preece, J.Samphire, J. Ramos-Soriano, A. Mauleon Amieva, M. E.Holbrow-Wilshaw, H. R. Gordon Newman, S. L. Kou, S. Medina-Villar, N. Dorh, J. Ndoa Dorh*, J. Spencer* and M. C. Galan*

"Fast Identification and Quantification of Uropathogenic E. coli through Cluster Analysis"

​ACS Biomater. Sci. Eng. (2022), 8, 1, 242–252

  DOI: 10.1021/acsbiomaterials.1c00732

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2021

100. J. Ramos-Soriano* and M. C. Galan* 

"Photoresponsive Control of G-Quadruplex DNA Systems"

J. Am. Chem. Soc. Au (2021), 1, 10, 1516–1526

  DOI: 10.1021/jacsau.1c00283

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99. A. Harland*X. LiuM. GhirardelloM. C. GalanC. M. Perks and K. M. Kurian*

"Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies"

Front. Oncol. (2021) 11:743814.

  DOI: 10.3389/fonc.2021.743814

 

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98. M. Ghirardello*, J. Ramos-Soriano and M. C. Galan*

"Carbon Dots as an Emergent Class of Antimicrobial Agents"

 Nanomaterials (2021), 11(8), 1877

DOI: 10.3390/nano11081877

 

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97. Y.-Y. Zhang, M. Ghirardello, T. Wang, A.-M. Luc, L. Liu, J. Voglmeir*, and M. C. Galan*

 

"Imidazolium labelling permits the sensitive mass-spectrometric detection of N-glycosides directly from serum"

 Chem. Common. (2021),  57, 7003-7006

DOI: 10.1039/D1CC02100A

 

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95. B. Hou*, D. Benito-Alifonso, R.F. Webster, D. Cherns, M. Carmen Galan  and David J. Fermín,*

"Synthetic mechanism studies of Iron Selenides: An Emerging Class of Materials for Electrocatalysis"

Catalysts (2021), 11(6), 681

DOI: 0.3390/catal11060681

 

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96. G. S. Bulmer, A. P. Mattey, F. Parmeggiani, 

R. Williams, H. Ledru, A. Marchesi, L. S. Seibt, P. Both, K. Huang, M. C. Galan, S. L. Flitsch, 

A. P. Green, J. M. van Munster.

"A promiscuous glycosyltransferase generates poly-β-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymes"

 

Org. Biomol. Chem. (2021),19, 5529-5533 

 

Preprint: (2020) BioRxiv  

DOI:10.1101/2020.02.14.949545

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94. B. Calle, G. Bineva-Todd, A. Marschesi, H. Flynn,

M. Ghirardello, O. Y. Tastan, C. Roustan, J. Choi,

M. C. Galan, B. Schumann and S. A. Malaker.

"Benefits of Chemical Sugar Modifications Introduced by Click Chemistry for Glycoproteomic Analyses"

J. Am. Soc. Mass Spectrom., 2021, 32, 9, 2366

 

DOI: 10.1021/jasms.1c00084

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93. J. Ramos-Soriano*, S. Benitez-Benitez,

A. P. Davis and M. C. Galan*

"A Vibration‐Induced Emision‐Based Fluorescent Chemosensor for the Selective and

Visual Recognition of Glucose"

Angew. Chem. Int. Ed., 2021, 60, 1-6 (Hot paper)

 

DOI: 10.1002/anie.202103545

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92. S. T. G. Street, P. Peñalver, M. P. O'Hagan,

G.J. Hollingworth, J. C. Morales* and M. C. Galan*

"Imide Condensation as a Strategy for the Synthesis of Core Diversified G-Quadruplex Ligands with Anti-Cancer and Anti-Parasitic Activity"

 

Chem. Eur. J., 2021, 27,1-11.

DOI:10.1002/chem.202100040

 

Preprint: (2020) ChemRxiv. 

DOI: 10.26434/chemrxiv.11955870.v1

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91. M. P. O’Hagan, S. Haldar, J. C. Morales,

A. J. Mulholland* and M. C. Galan*

"Enhanced sampling molecular dynamics simulations correctly predict the diverse activities of a series of stiff-stilbene G-quadruplex DNA ligands"

Chem. Sci., 2021,12, 1415-1426.

 

DOI: 10.1039/D0SC05223J

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90. S. Richards, T. Keenan, J-B. Vendeville,

D. E. Wheatley, H. Chidwick, D. Budhadev,

C. E. Council,C. S. Webster, H. Ledru, A. N. Baker,

M. Walker, M. C. Galan, B. Linclau,

M. A. Fascione and M. I. Gibson

"Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands"

Chem. Sci., 2021,12, 905-910.

 

DOI: 10.1039/D0SC05360K.

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2020

89. D. E. Wise, A. J. Gamble, S. W. Arkawazi,

P. H. Walton, M. C. Galan, M. P. O'Hagan, K. G. Hogg,

J. L. Marrison, P. J. O'Toole, H. A. Sparkes,

J. M. Lynam and P. G. Pringle

"Cytotoxic (cis,cis-1,3,5-triaminocyclohexane) ruthenium(II)-diphosphine complexes; evidence for covalent binding and intercalation with DNA"

Dalton Trans., 2020, 49, 15219-15230.

DOI: 10.1039/D0SC05360K.

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88. R. A. Jeanneret, S. E. Johnson and M. C. Galan*

 

"Conformationally Constrained Glycosyl Donors as Tools to Control Glycosylation Outcomes"

J. Org. Chem., 2020, 85, 15801 - 15826.

DOI/10.1021/ACS.JOC.0C02045

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87. R. A. Jeanneret and M. C. Galan*, 

 

"Ionic Liquid Tags for Supported Oligosaccharide Synthesis"

Reference Module in Chemistry,

Molecular Sciences and Chemical Engineering (2021) 2,  602

DOI:10.1016/B978-0-12-819475-1.00014-6

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85. A. J. Fairbanks*, Sabine L. Flitsch*, M. C. Galan* 

"Introduction to Glycosylation: new methodologies and applications". 

Org. Biomol. Chem., 2020, 18, 6979-6982.

DOI: 10.1039/D0OB90110E

84. T. A. Swift, D. Fagan, D. Benito-Alifonso, S. A. Hill, M. L. Yallop, T. A. A. Oliver, T. Lawson, 

M. C. Galan*, H. M. Whitney*

"Photosynthesis and crop productivity is enhanced by glucose-functionalized fluorescent carbon dots"

New Phytologist , 2020, 29, 783–790.

 Accepted.DOI:10.1111/nph.16886, 

Preprint: (2019)  BioRxiv DOI: 10.1101/82662

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83. E. Flack, H. Chidwick, G. Guchhait, T. Keenan, D. Budhadev, K. Huang, P. Both, J. Mas Pons, H. Ledru,

S. Rui, G. Stafford, J. Shaw, M. C. Galan, S. Flitsch, G.Thomas, M. Fascione*

"Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac Containing Glycosides"

ACS Catal., 2020, 10, 17, 9986–9993. 

DOI:10.1021/acscatal.0c02189

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82. S.S.E. Michel, A. Kilner, J.-C. Eloi, S. E. Rogers,

W. Briscoe* and M. C. Galan*

"Norbornene-Functionalised Chitosan Hydrogels and Microgels via an Unprecedented Photo-Initiated Self-

Assembly for Potential Biomedical Applications"

 

ACS Appl. Bio. Mat., 2020, 3, (8), 5253–5262.

DOI:10.1021/acsabm.0c00629

Preprint: (2020) ChemRxiv DOI: 10.26434/chemrxiv.12340484.v1

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81. P. Valverde, J.-B. Vendeville, K. Hollingsworth, A. Mattey, T. Keenan, H. Chidwick, H. Ledru, K. Huonnic, K. Huang, M. Light, N. Turner, J. Jimenez-Barbero,

M. C. Galan, M. A. Fascione, S. Flitsch,* W. B. Turnbull,* and B. Linclau,*

 

"Chemoenzymatic synthesis of 3-deoxy-3-fluoro-L-fucose and its enzymatic incorporation into glycoconjugates" 

 

Chem. Commun., 2020, 56, 6408-6411. 

DOI: 10.1039/D0CC02209H

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80. V. Levario-Diaz, P. Bhaskar, M. C. Galan*

and A. Barnes. 

"Effect of acoustic standing waves on cellular viability and metabolic activity"

 

Scientific Reports (2020) 10(1):8493

DOI: 10.1038/s41598-020-65241-4

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79. I. Herrera-Gonzalez, E. M. Sanchez-Fernandez,

A. Sau, C. Native, J. M. Garcia Fernandez,

M. C. Galan* and C. Ortiz Mellet*

 

"Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis"

 

J. Org. Chem., 2020, 85, 7, 5038-5047. 

DOI: 10.1021/acs.joc.0c00324

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78. K. Huang,   A. Marchesi,   K. Hollingsworth,   

P. Both,   A. P. Mattey,   E. Pallister,   H. Ledru,   

S. Charnock,   M. C. Galan,   W. B.Turnbull,   

F. Parmeggiani*  and  S. L. Flitsch*  

 

"Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides" 

 

Org. Biomol. Chem., 2020, 18, 3142 - 3148. 

DOI:10.1039/D0OB00407C

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77. M. P. O'Hagan, J. Ramos-Soriano, S. Haldar, S. Sheik,

A. J. Mulholland, J.C. Morales and M. Carmen Galan*

 

"Visible-light photoswitching of ligand binding mode suggests G-quadruplex DNA as a target for photopharmacology" 

 

Chem. Commun., 2020, 56, 5186 - 5189.

 DOI:10.1039/D0CC01581D

"Biocompatible visible-light photoswitching of ligand binding mode indicates G-quadruplex DNA as a target for photopharmacology" 

Preprint: (2020) ChemRxiv. 

DOI:10.26434/chemrxiv.11845272.v2

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74. M. P. O'Hagan, P. Peñalver, R. S. L. Gibson 

J. C. Morales*, M. C. Galan*

"Stiff-stilbene ligands target G-quadruplex DNA and exhibit selective anticancer and antiparasitic activity"

Chem. Eur. J., 2020, 26, 6244 - 6233. 

DOI:10.1002/chem.201905753

Preprint: (2019) ChemRxiv. 

DOI:10.26434/chemrxiv.11413122.v1

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73. C. Palo-Nieto, A. Sau,  R. A. Jeanneret,  

P.-A. Payard,  M. Braga Martins-Teixeira, 

I. Carvalho, L. Grimaud  and M. C. Galan*

"Copper Reactivity Can be Tuned to Catalyse

the Stereoselective Synthesis

of 2-Deoxy Glycosides from Glycals"

Org. Lett., 2020, 22, (5), 1991-1996. DOI:10.1021/acs.orglett.9b04525

Preprint: (2019) ChemRxiv. DOI:10.26434/chemrxiv.9272684.v1

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2019

C. Doyle,  K. Higginbottom, T. A. Swift, M. Winfield, C. Bellas, D. Benito-Alifonso, T.  Fletcher, 

M. C. Galan, K. Edwards, H. M. Whitney" A simple method for spray-on gene editing in plants". (2019)  BioRxiv DOI: 10.1101/805036

72. S.A. Hill,§ S. Sheikh,§ Q. Zhang, L. Sueiro Ballesteros, A. Herman, S. A. Davies, D. J. Morgan, M. Berry, D. Benito-Alifonso, M. C. Galan*"Selective Photothermal Killing of Cancer Cells Using LED-Activated Nucleus Targeting Fluorescent Carbon Dots".  Nanoscale Adv. (2019), 1, 2840-2846. DOI:10.1039/C9NA00293F

71. S. S.E. Michel, F. Dutertre, M. Denbow, M. C. Galan* and W. Briscoe "Facile Synthesis of Chitosan-Based Hydrogels and Microgels through Thiol-Ene Photoclick Crosslinking"

ACS Appl. Biomat. (2019), 2, 8, 3257-3268. DOI:10.1021/acsabm.9b00218

70. M. O'Hagan*, J. C. Morales, M. C. Galan* "Binding and beyond: what else can G-quadruplex ligands do?" Eur. J. Org. Chem. (2019), 4995-5017 DOI:10.1002/ejoc.201900692 and Cover Feature

69. K. Huang, F. Parmeggiani, H. Ledru, K. Hollingsworth, J. Mas Pons, A. Marchesi, P. Both, A. P. Mattey, E. Pallister, G. S. Bulmer,  J. M. van Munster,  W. B. Turnbull, M. C. Galan,* S. L. Flitsch* "Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant β1,4-galactosyltransferases" Org. Biomol. Chem. (2019), 17, 5920. DOI:10.1039/C9OB01089K

part of the themed collection: Chemical biology in OBC

68. M. Duchi, M.P. O’Hagan, R. Kumar, S.J. Bennie, M.C. Galan, B.F.E. Curchod and T.A.A. Oliver* "Exploring ultraviolet photoinduced charge-transfer dynamics in a model dinucleotide of guanine and thymine." Phys. Chem. Chem. Phys. (2019), 21, 14407. Photodissociation and reaction dynamics special issue. DOI: 10.1039/C8CP07864E

67. M.P. O’Hagan, S. Haldar, M. Duchi, T.A.A. Oliver, A. J. Mulholland, J.C. Morales and M.C. Galan*. "A photoresponsive stiff-stilbene ligand fuels the reversible unfolding of G-quadruplex DNA". Angew. Chem. Int. Ed. (2019), 131, 1. DOI:10.1002/anie.201900740

 

66. A. Sau, C. Palo-Nieto, M. C. Galan* “Substrate-controlled direct stereoselective synthesis of deoxyglycosides from glycals” J. Org. Chem. (2019), 84, 2415. DOI: 10.1021/acs.joc.8b02613 

2018

65.  I. Sittel, M.C. Galan* "Application Of Ionic Liquid And Fluorous Tags In Oligosaccharide Synthesis". Book Chapter in "Protecting Groups - Strategies and Applications in Carbohydrate Chemistry" S. Vidal editor, Wiley-VCH publishers. Release date: Dec. 2018. ISBN: 978-3-527-34010-1

64. T.A. Swift, T.A.A. Oliver, M.C. Galan, H.M. Whitney. "Functional nanomaterials to augment photosynthesis: evidence for future applications in food security" (2018) Interface Focus 9: 20180048. DOI:10.1098/rsfs.2018.0048

63. C. S. Bennett* and M. C. Galan*. “Methods for 2-Deoxyglycoside Synthesis.” Chem. Rev., 2018, 118, 7931. DOI: 10.1021/acs.chemrev.7b00731

62. D. Benito-Alifonso, B. Richichi, V. Baldoneschi,M. Berry,M. Fragai, G. Salerno, M. C. Galan,* and C. Nativi* “Quantum Dot-based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases (MT-MMPs).” ACS Omega 2018, 3, 9822. DOI: 10.1021/acsomega.8b00633

 

61. S. A. Hill, D. Benito-Alifonso, S. A. Davis, D. J. Morgan, M. Berry, and M. C. Galan* “Practical Three-Minute Synthesis of Acid-Coated Fluorescent Carbon Dots with Tuneable Core Structure” Scientific Reports, 2018, 8,12234. DOI:10.1038/s41598-018-29674-2 

60. T. A. Swift, M. Duchi, S. A. Hill, D. Benito-Alifonso, R. L. Harniman, S. Sheikhac, S. A. Davis, A. M. Seddon, H. M. Whitney, M. C. Galan* and T. A. A. Oliver*.“Surface nanoparticle functionalization affects the physical and electronic structure of fluorescent carbon dots.” Nanoscale, 2018, 10, 13908.

DOI: 10.1039/C8NR03430C Nanoscale top 5% most-read Q3

2017

59. C. Palo-Nieto, A. Sau and M. C. Galan* "Gold(I)-Catalysed Direct Stereoselective Synthesis of Deoxyglycosides from Glycals" J. Am. Chem. Soc.  2017, 139, 14041. Featured in Synfacts 

58. R. Williamns and M. C. Galan*. "Recent Advances in Organocatalytic Glycosylations" Eur. J. Org. Chem.  2017, 6247. EurJOC Readers‘ Choice 2019 

 

57. A. Sau and M. C. Galan*. "Palladium-Catalyzed α-Stereoselective O-Glycosylation of O(3)-Acylated Glycals" Org. Lett. 2017, 19, 2857.  

 

56. K. Röttger, H.J.B. Marroux, A. F. M. Chemin, E. Elsdon, T. A. A. Oliver, S. T. G. Street, A. S. Henderson, M. C. Galan, A. J. Orr-Ewing*, and G. M.Roberts*. "Is UV-induced. Electron-Driven Proton Transfer Active in a Chemically Modified A.T DNA Base Pair?"     J. Phys.Chem. B. 2017, 121 (17), 4448. 

 

55. I. Sittel and M. C. Galan*. "Imidazolium-labeled Glycosides as Probes to Harness Glycosyltransferase Activity in Human Breast Milk".  Org. Biomol. Chem. 2017, 15, 3575. Published in themed collection 2017 Hot Articles in Organic and Biomolecular Chemistry. Also featured in OBC Blog - https://rsc.li/2qbTWdA 

54. S. A. Hill and M. C. Galan*. "Fluorescent Carbon Dots from Mono- and Polysaccharides: Synthesis, Properties and Applications". Beilstein J. Org. Chem. 2017, 13, 675.  

53. S. T. G. Street, D. N. Chin, G. J. Hollingworth, M. Berry, J. C. Morales* and M. C. Galan*. "Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K+ Buffer". Chem. Eur. J. 2017, 23, 6953.

 

52. B. T. Miles, A. B. Greenwood, D. Benito-Alifonso, H. Tanner, M. C. Galan, P. Verkade and H. Gersen*. "Direct Evidence of Lack of Colocalisation of Fluorescently Labelled Gold Labels Used in Correlative Light Electron Microscopy" Scientific Reports. 2017, 7, 44666.

 

51.  A. Sau, R. Williams, C. Palo-Nieto, A. Franconetti, S. Medina and M. C. Galan* "Palladium-Catalysed Direct Stereoselective Synthesis of Deoxyglycosides from Glycals" Angew. Chem. Int. Ed. 2017, 56, 640. 

 

50. C. Palo-Nieto, A. Sau, R. Williams and M. C. Galan* “Cooperative Brønsted Acid-Type Organocatalysis for the Stereoselective Synthesis of Deoxyglycosides."  J. Org. Chem. 2017, 82, 407. 

49. D. Benito-Alifonso, M.C. Galan* "Bronsted and Lewis Acid Catalyzed Glycosylation". Book Chapter in "Selective Glycosylations - Synthetic Methods and Catalysts" C. Bennet  editor, Wiley-VCH publishers. 2017, ISBN: 978-3-527-33987-7. 

2016

48. S. A. Hill, D. Benito-Alifonso, D.J. Morgan, S.A. Davis, M. Berry, M. C. Galan*  "Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery". Nanoscale 2016 , 8, 18630. 

47. S. Medina, M. J. Harper, E. I. Balmond, S. Miranda, G. E. M. Crisenza, D. Coe, E. McGarrigle and M. C. Galan* "Stereoselective Glycosylation of 2-Nitrogalactals Catalysed by a Bifunctional Organocatalyst" Org. Lett. 2016, 18, 4222. 

46. T. S. Carter, T. J. Mooibroek, P. F. N. Stewart, M. P. Crump, M. C. Galan and A. P. Davis. "Platform Synthetic Lectins for Divalent Carbohydrate Recognition in Water". Angew. Chem. Int. Ed. 2016, 55, 9311. 

45.  A. S. Henderson, C. Pifferi and M. C. Galan*. "Synthesis of methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α- and β-D-glucopyranosides". In Carbohydrate Chemistry: Proven Synthetic Methods,” Volume 4, P. V. Murphy Ed., CRC Press, 2016.

44. A. S. Henderson, J. Bower* and M. C. Galan*. "Carbohydrate as Enantioinduction Components in Stereoselective Catalysis". Org. Biomol. Chem. 2016, 14, 4008.

 

43. D. Benito-Alifonso, S. Tremel, J. Sadler, M. Berry* and M. CarmenGalan*. "Imidazolium-Tagged Glycan Probes for Non-covalent Labeling of Live Cells". Chem. Commun. 2016, 52, 4906 - 4909.

 

42. R. Beattie, T. Hornsby, G. Craig, M. Carmen Galan* and C. L. Willis*. "Stereoselective Synthesis of Protected L- and D-Dideoxysugars and Analogues via Prins Cyclisations. Chem. Sci., 2016, 7, 2743-2747.

 

41. S. Medina and M. Carmen Galan*. "Recent developments in the stereoselective synthesis of deoxy glycosides". Carbohydr. Chem. 2016, 41, 59–89.

2015

40. K. Röttger, H. J. B. Marroux M. P. Grubb, P. M. Coulter, H. Böhnke, A. S. Henderson, M. C. Galan, F. Temps*,A. J. Orr-Ewing* and G. M. Roberts*. "Ultraviolet Absorption Induces Hydrogen-Atom Transfer in G⋅C Watson–Crick DNA Base Pairs in Solution". Angew. Chem. Int. Ed. 2015, 54, 14719-14722. 

 

39. A. S. Henderson, S. Medina, J. Bower* and M. C. Galan*. "Nucleophilic aromatic substitution (SNAr) as an approach to challenging carbohydrate-aryl ethers" Org. Lett. 2015,17 (19), 4846–4849.

 

38. I. Sittel and M. C. Galan*. "Chemo-enzymatic Synthesis of Imidazolium-Tagged Sialyllactosamine Probes" Bioorg. Med. Chem. Lett. 25, 2015, 4329-433.

37. S. Medina, A. Henderson, J. Bower and M. C. Galan*. "Stereoselective Synthesis of Glycosides using (salen)Co catalysts as promoters" Chem. Commun. 2015, 51, 8939-8941.

2014

36. A. S. Henderson, J. Bower* and M. C. Galan*, "Carbohydrate-Based N-Heterocyclic Carbenes for Enantioselective Catalysis"  Org. Biomol. Chem., 2014, , 12, 9180 – 9183.

 

35. E. I. Balmond, D. Benito-Alifonso, D. M. Coe, R. W. Alder, E. M. McGarrigle,* M. C. Galan* "3,4-Trans-Fused Cyclic Protecting Group Helps Achieve α-Selective Catalytic Synthesis of 2-Deoxyglycosides". Angew. Chem. Int. Ed. 2014, 53, 8190 –8194.

34. B. Hou, D. Benito-Alifonso, R. Webster, D. Cherns, M. C. Galan, D. J. Fermín* "Rapid Phosphine-Free Synthesis of CdSe Quantum Dots:  Promoting the Generation of Se Precursors by a Radical Initiator". J. Mat. Chem. A. 2014, 2, 6879-6886.

 

33. D. Benito-Alifonso, S.Tremel, B. Hou, H. Lockyear, J. Mantell, D. Fermin, Paul Verkade, M. Berry* and M. C. Galan*. "Lactose as a “Trojan Horse” for Quantum Dot Cell Transport".  Angew. Chem. Int. Ed. 2014, 53, 810-814. (Highlighted as a Hot Paper) 

 

32. E. I.  Balmond, E. McGarrigle* and M. C. Galan*. "N,N'-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea"  (2014) e-EROS [Online], John Wiley & Sons Ltd., https://onlinelibrary.wiley.com/book/10.1002/047084289X. 

2013

 

31. B. Hou, D. Benito-Alifonso, Nessrin Kattan, David Cherns, M. Carmen Galan and D. J. Fermín*. "Initial stages in the formation of Cu2ZnSn(S,Se)4 nanoparticles" Chem. Eur. J. (2013), 19, 15847 – 15851

30. D. Benito-Alifonso, R. A. Jones, A.-T.Tran, H. Woodward, N. Smith and M. Carmen Galan*. "Synthesis of mucin-type O-glycan probes as aminopropyl glycosides" Beilstein J. Org. Chem. (2013), 9, 1867–1872.


29. E. I. Balmond, M. C. Galan* and E. McGarrigle* "Recent Developments in the Application of Organocatalysis to Glycosylations" Synlett,  (2013); 24(18): 2335-2339.

 

28. M. C. Galan*, R. A. Jones and A.T. Tran, Recent Development of Ionic Liquids in Oligosaccharide Synthesis. The Sweet side of Ionic Liquids. (2013) Carbohydr. Res. (2013), 375 (2013) 35–46.

27. M. C. Galan, P. Dumy and O. Renaudet*, Multivalent Glyco(cyclo)peptides. Chem. Soc. Rev. (2013), 42, 459.

 

26. I. Sittel, A.T. Tran, D. Benito-Alifonso and M. C. Galan*, Combinatorial IOnic Catch and Release Oligosaccharide Synthesis (Combi-ICROS). Chem. Commun. (2013), 49 (39), 4217-4219.

2012

25. E. I. Balmond, D. M. Coe, M. C. Galan*, E. Mcgarrigle*,Alpha-Selective Organocatalytic Synthesis of 2-Deoxygalactosides. Angew. Chem. Int. Ed. (2012), 51, 36, 9152-9155. Highlighted in Synfacts (2012), 8 (10) 145.

24. M. C. Galan*, A.-T. Tran, K. Bromfield, S. Rabbani and B. Earnst. Chemo-enzymatic Synthesis of Ionic-Liquid Tagged Oligosaccharide Probes. Org. Biomol. Chem. (2012), 10, 7091-7097.


2011

23. M. C. Galan*, A. T. Tran, J. Boisson, D. Benito, C. Butts, J. Eastoe and P. Brown. [RN4] [AOT]: A surfactant ionic liquid as a mild glycosylation promoter. J. Carbohydr. Chem. (2011), 30, 486-497. Special Issue of the European Young Investigators Workshop on Carbohydrate Chemistry.

22. A. T. Tran, R. A. Jones, J. Pastor, J. Boisson, N. Smith and M. C. Galan*. Copper (II) triflate: a versatile catalyst for the one-pot preparation of orthogonally protected glycosides. Adv. Synth. Cat. (2011), 353 (14 - 15), 2593 - 2598.

21. A. T. Tran, R. Burden, T. D. Racys and M. C. Galan*. Ionic Catch and Release Oligosacharide Synthesis (ICROS). Chem. Commun. (2011), 47 (15), 4526 - 4528.


20. M. C. Galan*, D. Benito-Alifonso and G. M. Watt. Carbohydrate Chemistry in Drug Discovery. Org. Biomol. Chem. (2011), 9 (10), 3598 - 3610. Amongst the top ten most accessed articles during the month of March and May.

2010

19. M.C. Galan*, A.T. Tran, C. Bernard. Ionic Liquid based Catch and Release MS Tags for Enzyme monitoring.Chem. Commun. (2010) 46 (47), 8968 - 8970 

 

18. M. C. Galan* and Anthony P. Corfield. Ionic liquids in oligosaccharide synthesis: toward mucin type glycan probes. Biochem. Soc. Trans. (2010),38, 1368-1373.

17. R. A. Jones, R. A. Davidson, A. T. Tran, N. Smith and M. C. Galan*. Iodine catalyzed one pot acetalation-esterification reaction for the preparation of orthogonally protected glycosides. Carbohydr. Res. (2010), 345, 1842-1845 


16.   M. C. Galan*, A.T. Tran, S. Whitaker. [bmim][OTf] as co-Solvent/Promoter in Room Temperature Reactivity-Based One Pot Glycosylation Reactions. Chem. Comm. (2010) 46, 2106-2108

15.   M. C. Galan*, K. Jouvin, D. Alvarez-Dorta. Scope and Limitations of Imidazolium Based Ionic Liquids as Room Temperature Glycosylation Promoters. Carbohydr. Res. (2010) 345, 45-49

 

2009

14. M.C. Galan*, C. Brunnet, M. Fuensanta. [Bmim][OTf]: A Versatile Room Temperature Glycosylation Promoter. Tetrahedron Lett. (2009), 50, 442-445.



2000-2008

Publications with PhD and Post-doctoral Supervisors 

13. N. Yerkes, JX Wu, E. McCoy, M.C.Galan, S.Chen, S.E. O'Connor. Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis. Bioorg Med Chem Lett. (2008),18(10), 3095-8.

12. M.C. Galan, E. McCoy, S.E. O'Connor. Chemoselective derivatization of alkaloids in periwinkle. Chem. Comm (2007), 3249 - 3251. Highlighted as a Hot Paper by Chem. Comm.

11. S. Chen1, M.C. Galan1, C. Coltharp, S.E. O'Connor. Redesign of a central enzyme in alkaloid biosynthesis. Chem. Biol. (2006), 13, 1137-1141. 1Equal contribution.

10. E. McCoy, M.C. Galan, S.E. O'Connor. Substrate specificity of strictosidine synthase. Bioorg. Med. Chem. Lett. (2006) 16, 2475-8.

9. M.C. Galan, S.E. O'Connor. Semisynthesis of Secologanin Analogues. Tetrahedron Lett. (2006), 47 (10): 1563-1565. 

8. D Thayer, H.N. Yu, M.C. Galan, and C.H. Wong. A General strategy towards S-linked Glycopeptides. Angew. Chem. Int. Ed. (2005), 44, 29, 4596-4599.

7. M.C. Galan, A.P. Venot, and G.J. Boons. The Design and Synthesis of a Selective Inhibitor of Fucosyltransferase VI. Org. Biomol. Chem. (2004), 2, 1376-1380.

6. M.C. Galan, C.S. Dodson, A.P. Venot, and G.J. Boons. Glycosyltransferase Activity can be Selectively Modulated by Chemical Modifications of Acceptor Substrates. Bioorg. & Med. Chem. Lett. (2004), 14, 2205-2208.

5. M.C. Galan, A.P. Venot, J. Gluska, A. Imberty and Boons, G.J Chemo-Enzymatic Synthesis of Conformationally Constrained Oligosaccharides. Org. Biomol. Chem. (2003), 1, 3891-3899.

4. M.C. Galan, A.P. Venot, and G.J. Boons. Enzymatic Glycosylation of Conformationally Constrained Saccharides. Biochemistry (2003), 42, 8522 -8529.

3. M.C. Galan, A.P. Venot, J. Gluska, A. Imberty and Boons, G.J. alpha-(2,6)-Sialyltransferase Catalyzed Sialylations of Conformationaly constrained  Oligosaccharides. J. Am. Chem. Soc. (2002), 124, 5964-5973.
 
2. D. Lozano-Castello, D. Cazorla-Amoros, A. Linares-Solano, P.J. Hall, D. Gascon and C. Galan. In situ small angle neutron scattering study of CD4 adsorption under pressure in activated carbons. Carbon, (2001), 39, (9), 1343-1354.

1. C. Galan, L.E.A. Berlouis and P.J. Hall. The effects of electrochemical hydrogenation on coal structure: chemical and macromolecular changes; Fuel, (2000), 79, (12), 1431-1438.
 

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